Cinnamic acids and derivatives
![eMolecules 953769-46-5 | Sotuletinib | Ambeed | MFCD28142668 | 398.480 | C20H22N4O3S | 98.000 | CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1 | 1mg | 682927965](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502417835.JPG-250.jpg)
eMolecules 953769-46-5 | Sotuletinib | Ambeed | MFCD28142668 | 398.480 | C20H22N4O3S | 98.000 | CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1 | 1mg | 682927965
Sotuletinib | Ambeed | 953769-46-5 | MFCD28142668 | 398.480 | C20H22N4O3S | 98.000 | CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1 | 1mg | 682927965
Apexbio Technology LLC Tyrphostin 9 10537-47-0 10mM (in 1mL DMSO)
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
![Research Products International Corp Trans-Cinnamic Acid [B-Phenylacrylic acid], 25 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-C34400-25.0.JPG-250.jpg)
Research Products International Corp Trans-Cinnamic Acid [B-Phenylacrylic acid], 25 Grams
Auxin like growth regulator.
Cayman Chemical m-CoumarIc AcId 10g
An active metabolite of polyphenols; inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM); induces neurite outgrowth of fetal rat hippocampal neurons at 10 µM; induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cells at 5 and 10 mM, respectively; increases locomotor activity in mice at 3 mmol/kg
Medchemexpress LLC Tyrphostin AG 879 | 148741-30-4 | MFCD00236450 | 99.3% | 10 MG
Tyrphostin AG 879 is a small-molecule tyrosine kinase inhibitor widely used in laboratory research. It shows selectivity for ErbB2 (HER2) with a reported IC50 of about 1 μM and reduces TrkA phosphorylation at higher micromolar concentrations. The compound is supplied as a powder, is soluble in DMSO, and is intended for in vitro signaling and kinase pathway studies.
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 50 G
4-Methoxycinnamic acid is a natural phenylpropanoid found in A. preissii. This unique compound plays a role in phenylphenalenone biosynthesis. It is intended for research use only.
- Detected as a natural phenylpropanoid
- Involved in phenylphenalenone biosynthesis
- Suitable for research applications
Medchemexpress LLC 2-Methoxycinnamic acid | 6099-03-2 | 178.18 | 1 ML
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. It is for research use only.
- Purity: 99.94%
- Appearance: Solid, white to off-white
- Structure classification: Phenylpropanoids, Simple phenylpropanols
- Initial source: Plants (*Pulsatilla chinensis* (Bunge) Regel)
- Solubility (In Vitro): 100 mg/mL (561.23 mM) in DMSO (requires ultrasonication)
- Solubility (In Vivo): ≥ 2.5 mg/mL (14.03 mM) in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline (clear solution) or in 10% DMSO, 90% Corn Oil (clear solution)
Medchemexpress LLC 3,4-Dimethoxycinnamic acid | 2316-26-9 | 208.21 | 1 G
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.
- Attenuates the ethanol-induced apoptosis of ethanol-exposed L-02 cells
- Inhibits the expression levels of Nox4 and p22phox in L-02 cells
- Attenuates ethanol-induced MAPK phosphorylation in L-02 cells
- Decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase
- Downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner
Medchemexpress LLC Entacapone | 130929-57-6 | 99.97% | C14H15N3O5 | 50 MG
Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It is selective for COMT over other catecholamine metabolizing enzymes and can be used for Parkinson's disease research. Entacapone also inhibits FTO demethylation, making it relevant for metabolic disorders research.
- Inhibits COMT with IC50 values in the nanomolar range
- Demonstrates agonist activity at GPR35 in HT-29 and U2OS cells
- Enhances m6A on mRNA in Hep-G2 cells
- Decreases body weight and fat mass in obese mouse models
- Reduces total cholesterol, low-density lipoprotein cholesterol, and triglycerides
Medchemexpress LLC Trans-cinnamic acid-d7 | 343338-31-8 | 100.0% | 155.20 | C9HD7O2 | 10 MG
trans-Cinnamic acid-d7 is the deuterium-labeled analogue of trans-cinnamic acid, used as an internal standard and tracer in analytical chemistry and metabolic studies. It is supplied as a high-purity white to off-white solid intended for research applications.
- Deuterium-labeled for use as an internal standard in mass spectrometry and tracer studies.
- High reported purity (99.98%).
- White to off-white solid, stable under standard storage conditions.
- Suitable for analytical and metabolic research applications.
- Available in a 10 mg analytical-scale quantity.
Medchemexpress LLC P-coumaric acid (standard) | 501-98-4 | MFCD00004399 | 99.8% | 164.16 g/mol | C9H8O3 | 10 MG
p-Coumaric acid (trans-4-hydroxycinnamic acid) analytical standard supplied as a high-purity solid for research and analytical applications. It is intended for use as a reference for identification, quantification, and method validation in chromatographic and spectroscopic workflows.
- Analytical standard for identification and quantification
- High purity suitable for method validation
- Supplied as a 10 mg solid for convenient handling
- Compatible with HPLC, GC, and mass spectrometry methods
- Useful for calibration and quality control in research laboratories
TARGETMOL CHEMICALS INC POLYINOSINIC-POLYCYTIDYL 25MG
Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Polyinosinic-polycytidylic acid (Poly(IC)) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts as the most potent interferon (IFN) inducer. It also is a Toll-like receptor- 3 (TLR3) agonist. purity: 98%